O.S. Sychov, T.V. Mikhalieva.Non-valvular atrial fibrillation in patients with age less than 65 years and preserved left ventricular systolic function: clinical features and myocardial remodeling

The aim – to study the clinical characteristics and types of left ventricle (LV) remodeling in patients with non-valvular atrial fibrillation (AF), age less thаn 65 years and preserved LV systolic function.
Material and methods. We enrolled 161 patients with non-valvular AF, associated mainly with essential hypertension (EH), coronary heart disease (CAD), EH combined with CAD, and myocardial fibrosis. Among them 55 (34.2 %) patients had paroxysmal AF, 81 (50.3 %) – persistent (including 8 with long persistent) and 25 (15.5 %) – stable.
Results. Stable AF, comparing with paroxysmal and persistent forms, was associated with a higher frequency of stroke or transient ischemic attack, higher frequency of patients with high and very high additional risk of EH complications, as well as clinically manifest heart failure (NYHA II and III).
Conclusions. Frequency of LV remodeling types was comparable in different forms of AF. LV remodeling was most closely associated with the presence of EH.

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