O.S. Sychov, A.O. Borodai, S.V. Fedkiv, E.S. Borodai, T.V. Getman, A.Yu. Rybak.Рredictors of silent cerebral infarctions of cardioembolic origin in patients with non-valvular atrial fibrillation.

The aim – to evaluate prevalence of silent cerebral infarctions (SCI) of cardioembolic origin and its predictors in patients with persistent atrial fibrillation (AF).
Material and methods. We examined 134 patients with non-valvular AF. All patients underwent anamnesis, neurological, biochemical examinations, transesophageal, transthoracic echocardiography and brain multispiral computed tomography.
Results. Silent cerebral infarcts were detected in 46 (34.33 %) patients, and infarcts ≥ 15 mm (mean diameter 31.3 mm) – in 15 (11.19 %) patients. According to the multivariate analysis, CHA2DS2-VASc score was an independent predictor of superficial SCI; low atrial appendage velocity < 30 cm/s was independently associated both with SCI ≥ 15 mm (Р=0.03) and superficial SCI (Р=0.02). Conclusions. Silent cerebral infarctions are not uncommon in patients with AF. Large and superficial SCI in the absence of atherosclerosis of carotid and/or large brain arteries commonly have embolic source.

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