O.Ye. Berezin, T.O. Samura Brain natriuretic peptide as early marker of remodeling after myocardial infarction: outcomes of a cohort study.

Eighty five patients (males and females) with documented Q-wave myocardial infarction (MI) were observed during 60 days after hospitalization due to the index event. Clinical features, cardiac hemodynamics and serum
NТ-pro-BNP levels were measured at admission, 21 and 30 days after beginning of the MI. Analysis of data showed that NТ-pro-BNP measurements at admission have predictive value for early cardiac remodeling and systolic left ventricular dysfunction after myocardial infarction. In multivariate analysis, NТ-pro-BNP appeared as a predictor of cardiac remodeling which was independent of GRACE risk score and local systolic dysfunction.

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