О.J. Zhаrіnоv, Yu.І. Zаlіznа, К.О. Міkhаlev, V.О. Кuts.Clinical features and course of first-detected non-valvular atrial fibrillation

The aim – to compare clinical symptoms, concomitant diseases, myocardial structure and function parameters in patients with first-detected atrial fibrillation (AF) depending on further course of arrhythmia.

Material and methods. The study group included 124 patients, including 49 with spontaneous restoration of sinus rhythm up to 7 days (paroxysmal AF), 30 in which cardioversion was performed (persistent AF) and 45 with first-detected permanent AF. We evaluated symptoms, cardiovascular disease, risk factors, comorbidities, renal and thyroid function, results of echocardiography.

Results. Groups of patients with recurrent forms of AF were characterized by more severe palpitations, higher heart rate, lower levels of thyroid-stimulating hormone and glycosylated hemoglobin. In contrast, in patients with permanent AF form palpitation was less important and the clinical picture was dominated by symptoms of heart failure. Patients with paroxysmal AF were older, were characterized by pronounced changes in myocardial structure and function parameters and higher risk of thromboembolic complications, while the formation of the first episode of persistent AF was less associated with chronic myocardial pathology and heart failure.

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