O.S. Sychov, A.A. Borodai, T.V. GetmanClinical predictors of the left atrial appendage dysfunction in patients with non-valvular atrial fibrillation.

National Scientific Center “M.D. Strazhesko Institute of Cardiology NAMS of Ukraine”, Kyiv, Ukraine
The aims – to determine association between severe left atrial appendage dysfunction and CHA2DS2VASc score.
Materials and methods. The overall 303 patients with persistent and long persistent were examined consecutively by transesophageal echocardiography. In addition to measurement of the left atrial appendage velocity (LAAV), the atrial appendage was examined for the presence of spontaneous echo contrast (SEC) or thrombi. Results. Severe SEC 4+ was found in 7.09 % of cases, LAA thrombi – in 6.71 % and LAAV ≤ 25 cm/s – in 24.32 % of patients. We found that CHA2DS2VASc score ≥ 2 was significantly associated with LAAV ≤ 25 cm/s (OR 2.18; 95 % CI 1.76–2.6; P=0.007) and SEC 4+ (OR 4.93; 95 % CI 4.37–5.47; Р=0.006). CHA2DS2VASc score ≥ 4 was significantly associated with LAA thrombi (OR 3.1; 95 % CI 2.13–4.06; P=0.033). Conclusion. In patients with CHA2DS2VASc score ≥ 2 transesophageal echocardiography must be performed because of significantly increased risk of severe LAA dysfunction in this group.

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