Yu.V. Zinchenko, A.P. Stepanenko, Valizade Chary Jafar Influence of background antiarrhythmic therapy upon efficacy of electric cardiac stimulation in isolated atrial flutter lasting less than 7 days.

We performed 161 transesophageal electric cardiostimulation (TEECS) procedures in order to restore sinus rhythm in isolated non-valvular type I atrial flutter (AF) lasting less than 7 days in 153 (95 %) men and 8 (5 %) women with CAD (137 patients) and myocardial fibrosis (24 patients). Arterial hypertension was diagnosed in 122 (75,8 %) patients. Mean duration of AF paroxysm constituted 2.9±0.1 days. With the aim of evaluation of
influence of background antiarrhythmic treatment (AAT) upon TEECS efficacy all patients were divided into two groups: in group 1 (n=88) cardioversion was performed with background AAT, in group 2 (n=73) no AAT was
administered. According to our study results TEECS appeared to be highly effective and safe method of cardioversion in isolated type I AF, regardless of background AAT (95.5 % of successful sinus rhythm restoration
with AAT, and 100 % – without AAT prior to TEECS, р>0.05). Therefore, the procedure may be performed without preliminary AAT preparation. Also, no difference was found between the groups regarding direct result of
stimulation during sinus rhythm restoration (26.1 % vs. 23.3 %, respectively, р>0.05), sinus rhythm restoration through atrial fibrillation episode (63.6 % vs. 72.6 %, respectively, р>0.05), delayed sinus rhythm restoration during 24 hours after procedure (3.4 % vs. 1.4 %, respectively, р>0.05), necessity in procainamide administration in case of post-stimulation atrial fibrillation (21.2 % vs. 20.5 %, respectively, р>0.05), which witnesses no influence of background AAT upon electric cardiac stimulation results.

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