M.M. Dolzhenko, A.Ya. Bazylevich, N.M. Nosenko Influence of non-alcoholic fatty liver disease on course of ischemic heart disease during two-years observation.

We performed a prospective research of the influence of non-alcoholic fatty liver disease (NAFLD) in 315 patients with coronary artery disease (CAD) after acute myocardial infarction during two years of observation.
All patients have been divided into two groups. The first group consisted of 214 patients (68 %), who had CAD with concomitant NAFLD (CAD+NAFLD). The second, the control group, consisted of 101 persons (32 %) –
patients with CAD without NAFLD. The research revealed worsened course of CAD in patients with NAFLD. Patients with CAD+NAFLD had adverse prognosis, i.e. significantly more prevalent bypass occlusion, the progression of heart failure, vital ventricular arrhythmias. The risk of atrial fibrillation as a complication of coronary artery bypass surgery in group of CAD+NAFLD was 1.5 times higher than in group without NAFLD. In group with CAD+NAFLD total mortality was significantly higher compared to CAD without NAFLD during two years of observation.

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