I.А. Chaikovskii, М.P. Boichak, V.N. Sosnitskii, М.I. Lutai, L.А. Stadniuk, G.V. Мiasnikov, А.N. Lomakovskii, Т.V. Sosnitskaya, М.V. Bichko, Ye.K. Rykhlik, I.I. Gangal, B. Heiler Informativeness of the complex magnetocardiography parameter for diagnosis of obstructive coronary artery disease: results of the two-center study.

The aim of the paper is to investigate the predictive value of a newly developed magnetocardiography (MCG) index (CI) in the diagnosis of coronary artery stenosis in patients with intermediate pretest probability of ische mic heart disease and uninformative results of routine tests. The study group consisted of 79 patients without a history of myocardial infarction which underwent coronary angiography because of chest pain. Depending on the results of coronary angiography, this group was divided into two subgroups: with > than 70% stenosis in at least one of the coronary artery and without hemodynamically significant stenosis. Control group consisted of 30 healthy volunteers. All examined persons underwent MCG-examination by 7-channel MCG system installed in unshielded setting. Integrated MCG-index (CI) was calculated. It was shown that CI was significantly higher in patients with significant stenosis compared with patients without stenosis and with healthy subjects. Parameters of the diagnostic value of the test were following: sensitivity – 93%, specificity – 84%, positive predictive value – 85%, negative predictive value – 93%. In conclusion, the MCG test at rest might be recommended as a method of choice for the diagnosis of significant coronary artery stenosis in patients with intermediate pretest probability of the disease.

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