The purpose of the review is to evaluate the available data from fundamental and clinical studies indicating that posttraumatic stress disorder and adjustment disorders are independent risk factors of cardiovascular pathology. Smoking, hypodynamia, alcohol abuse, drug addiction, obesity on the background of behavioral eating disorders partially cause an increase of the cardiovascular risk. The main mechanisms for implementing this association are discussed. The links between mental disorders and diseases of the circulatory system are confirmed by general candidate genes. These factors must be taken into account while assessing personal cardiovascular and mental risks, as well as creating effective preventive and therapeutic measures.