S.M. Kozhukhov, O.M. Parkhomenko.Scientific evidence of efficiency of еplerenone in patients with left ventricular dysfunction: from myocardial infarction to heart failure

Aldosterone plays a major pathophysiological role in post-myocardial infarction cardiac remodeling and heart failure. Therefore blockers of the aldosterone receptors such as eplerenone have gained widespread use in the treatment of myocardial infarction with heart failure and chronic heart failure. The article outlines the clinical evidence on the efficacy of eplerenone in heart failure and clinical perspectives for its use.

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