О.O. Kvasha, I.P. Smirnova, I.M. Gorbas, O.V. Sribna Dynamics in the structure of lipid factor of cardiovascular risk at 35 years follow-up among urban male population

The aim – to estimate the prevalence of hypercholesterolemia (HCh) and its dynamics according to the 35-years monitoring of the urban males risk profile.

Material and methods. In 2014–2015 years we examined 855 men aged 18–64 years. The obtained data were compared with results of similar design studies carried out in 1980 (n=1258), 2000 (n=1025), 2005 (n=998) and 2010 (n=1009).

Results. There were no changes in age-standardized prevalence rates of hypo-α-cholesterolemia (15.5–15.3 %). At the same time we’ve found a significant increase in HCh from 46.7 to 60.3 % (Р<0.01) and high and very high levels of cholesterol LDL – from 24.3 to 58.2 % (Р<0.001). The increase of average population cholesterol values ​​(from 5.21 to 5.76 mmol/L, Р<0.001), LDL cholesterol (from 3.34 to 4.09 mmol/L, Р<0.001) and decrease of HDL cholesterol (from 1.36 to 1.08 mmol/L, Р<0.01) were registered. Conclusion. The negative dynamics of lipid profile among urban men appears to be caused by the deterioration of the economic and socio-political situation in the country. Further studies are needed to understand the persistence of identified changes and evaluate their possible contribution to the development of future population health data.

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