We examined 200 patients with chronic heart failure (CHF) class II–IV NYHA in order to study the prognosis of survival over 6 and 12 months’ follow-up depending on ambulatory physical activity level and depressive
disorder severity as quality of life components in patients with CHF. Cluster analysis was used to stratify patients into subgroups with significant differences in survival. Further analysis of survival and statistical significance of differences between groups was performed. Hazard ratio (HR) was evaluated by Cox regression univariate analysis. Informative predictors of CHF patients’ non-survival over the following 6 months were overall scores according to the scale of ambulatory physical activity of Duke University > 4.5 (HR: 3.165), over 12 months > 3,625 points HR: 3.34). Informative predictors of patients’ non-survival over the following 6 months was depression level according to Beck scale > 14; HR: 2.818 (depression disorder of moderate grade), over the following 12 months > 6,5 points; HR: 2.273 (depression disorder of mild grade).