The aim – to demonstrate reliability, validity and responsiveness of the Russian version of the Atrial Fibrillation Effect on QualiTy-of-life (AFEQT) questionnaire for using it in patients with atrial fibrillation and flutter (AF-AFl).
Material and methods. The prospective, observational study was performed in 274 patients with non-valvular AF-AFl. Mean age was 61.4±9.7 years. Persistent arrhythmia was in 160 (58.4 %), long-lasting persistent form – in 20 (7.3 %), permanent form – in 61 (22.3 %) and paroxysmal – in 33 (12 %) patients. Participants completed AFEQT at baseline and 69 of them at ≥ 1 month.
Results. Internal consistency was > 0.85 for all scales. Lower AFEQT scores were observed with increased EHRA and NYHA classes. Patients with recurrence of AF had the same scores of general AFEQT 58.1± 20.9 vs 60.4±20.9 at follow-up. Patients with sinus rhythm at time of follow-up had significantly better AFEQT 50.8±19.6, vs 65.8±23.5 (Р=0.005). Significant changes were found in all domains of AFEQT and their effect sizes were consistent with moderate or large clinical changes.
Conclusions. Initial validation of the Russian version of AFEQT supports its use as an outcome in clinical studies and as additional means to clinically follow patients with AF.