О.S. Sychov, А.О. Borodai. Validation of the russian version of AF-QoL questionnaire in patients with non-valvular atrial fibrillation and flutter

The aim – to demonstrate reliability, validity and responsiveness of the Russian language version of the AF-QоL questionnaire using it in patients with atrial fibrillation and flutter (AF – AFl).

Material and methods. In prospective observational study, we evaluated 288 patients with non-valvular AF – AFl. Mean age was 61.4±9.9 years. Persistent arrhythmia was registered in 167 (58.0 %), long-lasting persistent form in 21 (7.3 %), permanent form – in 63 (21.9 %) and paroxysmal – in 37 (12.8 %) patients. Participants completed AF-QоL at baseline and 75 of them at ≥ 1 month.

Results. Internal consistency was > 0.81 for all scales. AF-QоL had reasonably good convergent and divergent validity. Lower AF-QоL scores were observed along with increased EHRA and NYHA classes. Contrary to patients with recurrence of AF – AFl, patients with sinus rhythm had significantly better global and physical AF-QоL (41.4±18.8 vs 53.0±19.1, Р=0.01, and 35.7±21.5 vs 51.7±23.6, Р=0.003, respectively). Such changes translated into an effect sizes were consistent with moderate clinical changes.

Conclusions. Initial validation of russian version of AF – AFl supports possibility of its use as an instrument for measurement of health-related quality of life in patients with AF – AFl.

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