O.I. Mitchenko, A.V. Rudenko, M.M. Gelmedova, V.Yu. Romanov, V.V. Gutovskyi The features of individual history, hypertension and carbohydrate metabolism disorders in patients with multiple coronary atherosclerosis before coronary artery bypass grafting.

The aim of the study was to assess characteristics of individual history, hypertension and carbohydrate metabolism disorders in patients with multiple coronary atherosclerosis before coronary artery bypass grafting. We included 85 patients (71 men and 14 women) with multiple coronary atherosclerosis. The anamnesis was characterized by high prevalence of major cardiovascular events history (70.6% – myocardial infarction, 7.1% –
cerebrovascular accidents), which occurred in 100% of cases on background of hypertension and in 85% – previous silent forms of coronary artery disease. This was due to inclusion of large number of patients with
impaired carbohydrate metabolism (84%), such as diabetes mellitus (DM) (95.8%) and pre-diabetes (4.1%). At the preoperative examination first detected DM was registered in 7.2% of patients and in 62.3% of patients
with DM was decompensated. After correction of the glycemic status mean glucose level in patients before revascularization was 6.54±0.18 mmol/l. Hypertension in this patients was mainly controlled, with unfavorable circadian profile of blood pressure (non-dippers – 50.6%, night-peakers – 13,6%). After correction of antihypertensive therapy systolic office blood pressure was 121.62±0.87 mm Hg, and diastolic blood pressure – 78.94±0.47 mm Hg. So, a detailed examination of patients with multivessel coronary atherosclerosis before coronary artery bypass grafting showed a large percentage of improperly adjusted cardiovascular risk factors.

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