L.G. Voronkov, L.P. Paraschenyuk, P.M. Babych The predictive significance of total score indices of the Physical Health Component of Living Quality Questionnaire SF-36 in patients with chronic heart failure of III functional class NYHA.

In order to study the survival rate during 1st, 2nd, 3rd and 5th years depending on the total score indices of the Physical Health Component Living Quality Questionnaire SF-36, 554 patients with chronic heart failure of III functional class after NYHA were evaluated. During the first research stage the sub-groups of patients were selected by means of cluster analysis (k-average method). They were not overlapping by values of the Physical Health Component Questionnaire SF-36 indicator and at the same time were definitely dissimilar regarding cumulative survival during 1st, 2nd, 3rd and 5th years. The indicated sub-groups were homogeneous by such
indices as value of left ventricular ejection fraction, percentage of patients receiving angiotensin converting enzyme inhibitors and beta-adrenoreceptor blockers. During the second stage the relative risk was calculated
by Cox regression of fatal end for the patient clusters with range of values of overall life quality index, which was associated with reliable inferior survival during each of the given investigation period. The study of long-term survival of chronic heart failure patients found out the dependence on the overall index of the Physical Health Component Living Quality Questionnaire SF-36. The overall score of the Questionnaire SF-36 . 37.5 is the survival predicting factor for patient with chronic heart failure of III functional class after NYHA during 1st. 5th years of observation irrespectively of the value of left ventricular ejection fraction, usage of angiotensin converting enzyme inhibitors and beta-adrenoreceptor blockers. The predicting factor of the Questionnaire SF-36 less than 37.5 is the most comprehensive in predicting fatal end during next 1st and 2nd years of followup period (relative risk values 1.78 and 1.97, respectively).

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