L.N. Babii, N.P. Stroganova, S.Yu. Savitskiy, U.Yu. Ostapchuk, L.F. Kisilevich, Yu.O. Khomenko, I.K. Sledzevskaya.The relationship between exercise tolerance, functional state of left ventricle and blood aldosterone level in patients after myocardial infarction at prolonged follow-up

The aim of the article was to study exercise tolerance, functional state of left ventricle (LV), blood aldosterone level in 60 patients (pts) after Q-wave myocardial infarction (MI) at 2-year follow-up. Hemodynamic parameters were determined at echocardiography, 6-minute walking test was performed. First functional class (FC) and preserved LV systolic function (EF more than 50 %) at rest and during physical exercise were associated with normal blood aldosterone level. Patients with 2nd and 3rd FC and EF more than 45 % had blood aldosterone level increased by more than 1.5 times. Patients with 3rd FC and EF less than 45 % had blood aldosterone level increased by more than two times. Exercise tolerance was related to systolic function and aldosterone level.

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