Yu.V. Zinchenko, A.P. Stepanenko, Valizade Chary JafarInfluence of background antiarrhythmic therapy upon efficacy of electric cardiac pacing in isolated atrial flutter lasting over 7 days.

We performed 300 transesophageal electric cardiac pacing procedures (TEECS) in order to restore sinus rhythm in isolated non-valvular type I atrial flutter (AF) lasting over 7 days in 270 (90 %) men and 30 (10 %)
women with ischemic heart disease (224 (74.7 %) patients) and with myocardial fibrosis (76 (25.3 %) patients). Arterial hypertension was diagnosed in 198 (66 %) patients. Mean duration of AF episode constituted
65.2±3.8 days. In order to evaluate influence of background antiarrhythmic treatment (AAT) upon TEECS efficacy all patients were divided into two groups: in group 1 (n=237) cardioversion was performed with
background AAT, in group 2 (n=63) no AAT was administered. According to our study results TEECS appeared to be highly effective and safe method of cardioversion in isolated type I AF, regardless of background AAT
(89 % with AAT vs. 93.7 % without AAT, respectively, Р>0.05). In both groups patients showed comparable need for procainamide administration in case of post-stimulation atrial fibrillation (21.1 % vs. 23,8 %, respectively, Р>0.05); demonstrated delayed sinus rhythm restoration during 24 hours after procedure (8.9 % vs. 9.5 %, respectively, Р>0.05); had recurrent arrhythmia paroxysms (7.2 % vs. 12.7 %, respectively, Р>0.05) usually during next 7 days after successful cardioversion, which requires further anti-recurrent AAT administration during next 2 weeks.

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