L.G. Voronkov, O L. Filatova, A.V. Lyashenko, L.P. Parashchenyuk, N.A. TkachTwelve-months survival and its predictors in patients with chronic heart failure and reduced left ventricular ejection fraction in relation to gender

The aim – to compare 12-months survival and its predictors in men and women with chronic heart failure (CHF) and reduce left ventricular ejection fraction (LVEF).

Material and methods. 356 CHF patients with LVEF were examined. The 12-months survival by Kaplan – Meier method was calculated. Predictors of survival were calculated by Cox regression (univariate) model.

Results. Cumulative survival among men and women for 12 month were 91 % and 92 %, respectively (H=0,59). Predictors of survival in men were: the presence of angina pectoris, right ventricular wall thickness, LVEF, left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), LVEDV index, LVESV index, stroke volume, pulmonary artery average pressure, creatinine level, total cholesterol, estimated glomerular filtration rate. Predictors of 12-months survival in women were: LVEF, LVEDV, LVESV, and total bilirubin level.

Conclusions. Twelve-months survival in men and women with CHF and LVEF were similar. Predictors of 12-months survival in men and women are considerably different, the number of predictors being substantially more in men.

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