The aim – to study the effect of long-term (6 months) use of the drug for lipid and carbohydrate metabolism improvement in patients with metabolic disorders.
Material and methods. Open-label, non-comparative study included 30 men and women within 6 months of receiving drug for lipid and carbohydrate metabolism improvement (blueberry paste) in patients with metabolic disorders. Participants were examined at the start of the study, after 3 and 6 months of taking the paste. Study of lipids, glucose, C-reactive protein, prothrombin index was performed, anthropometric measurements were conducted, blood pressure was measured.
Results. Reduction of prothrombin index was registered after 3 months of taking bluberry paste, further usage had no effect on this index. After 6 months, a significant decrease in total cholesterol, LDL cholesterol and C-reactive protein at 9, 13 and 29 %, respectively, was recorded. A significant reduction in mean glucose levels from 5.26±0.12 to 4.58±0.14 mmol/l (P<0.001) was revealed. The influence of blueberry paste on body weight and blood pressure was not registered. Conclusions. The usage of the drug has positive impact on lipid and carbohydrate metabolism, resulting in a significant decrease in the content of cholesterol, LDL cholesterol, glucose and C-reactive protein and can be used for correction of lipid and carbohydrate metabolism both separately and in combination with primary treatment.