The aim of the study was to establish blood pressure variability (BPV) Chernobyl NPP accident clean-up workers (ChNPP ACUW) with arterial hypertension (AH). Among 315 men studied, 165 ChNPP ACUW constituted Group 1 including 36 persons having AH Grade I and 129 ones with AH Grade II. Group 2 included 62 patients not involved in clean-up activities after the Chernobyl accident. 88 ChNPP ACUW having no circulation disorders constituted the control group. BPV elevation was found in 77.7 % of ChNPP ACUW with AH, including 52.4 % of them regarding twenty-four hour BPV and 25.3 % nighttime BPV. Systolic BPV round the clock and at night both with diastolic BPV at nighttime were significantly exceeding the respective indices in persons from general population despite other parameters being comparable. Left ventricular hypertrophy and remodeling were associated with reliably higher BPV. Extended variability of systolic and diastolic blood pressure, especially at nighttime, makes great impact on myocardial dystrophy progress in ChNPP ACUW suffering AH. Identification of an increased BPV is an indicator of left ventricular hypertrophy development and severity.