M.I. Lutaі, I.P. Golikova Calcification of the aorta and coronary arteries in patients with chronic ischemic heart disease: age and gender characteristics, the relationship with risk factors

The aim – to evaluate relationship of coronary and aortic calcification and traditional risk factors in patients with coronary artery disease.

Materials and methods. There were 180 patients examined (69.4 % men, mean age 60.4±10.8 years). Cardiac multislice computed tomography with quantitative assessment of coronary and aortic calcification using «Smart Score» program was performed in all patients. The diagnosis of CHD was verified by сoronary catheterizationor or multislice computed tomography.

Results. Increase in coronary and aortic calcification along with age was found in both gender groups. The coronary calcium score was significantly higher (by 3 times) in men than in women of similar age. However, prevalence of calcium deposits in aorta was not significantly different in men and women.

Conclusions. Among traditional risk factors diabetes mellitus was associated with more severe coronary calcification, while hypertension was associated with aortic calcinosis. Coronary calcium score and level of calcium in aorta were significantly higher in patients with severe hypercholesterolemia (total cholesterol level ≥ 7.0 mmol/l). The relationship of other cardiovascular risk factors (smoking, peripheral atherosclerosis, family history) to coronary calcinosis was not significant.

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