Yu.N. Sokolov, M.Yu. Sokolov, V.I. Chubko, A.Yu. Sirenko, M.I. Studzinskaya Long-term results of stenting in patients with symptomatic chronic coronary occlusions

The aim of the study is to investigate long-term clinical efficiency of percutaneous revascularization of total chronic occlusions of coronary arteries in patients with coronary lesions. The study enrolled 272 patients with total chronic occlusions. Patients were divided into four groups. All patients enrolled in the study underwent diagnostic coronarography and ventriculography. Instrumental examination included: 12 lead rest ECG, ultrasound of the heart, coronarography. Basic medical therapy included different combinations of antianginal (beta-blockers, calcium channel blokers, angiotensin-converting enzyme inhibitors, nitrates) and antiplatelet drugs. In the group A (n=138) percutaneous coronary intervention (PCI) was performed and stenting was performed. Patients in group D (n=134) were defined as the control group and PCI was not performed. In
patients of group C (n=54) coronary ventriculography was performed and after discharge coronary artery bypass grafting (CABG) was performed. Patients of group B (n=80) received coronary ventriculography but PCI
or CABG was not perfomed. Kaplan–Meier method was implied for statistical analysis. As the result of 48 months follow up the survival rate in group A and group B was 94 % and 75 % and the significant statistic difference
(P=0.00002) was achieved. Results comparing PCI and CABG didn’t show any significant statistic difference (Р=0.5), and the survival rate was 93 % and 97 % during 48 months. There was no difference of the rate of
myocardial infarction during 48 months follow up. The study showed that the coronary stenting is effective and relatively safe method of treatment of patients with total chronic occlusions.

Full article